Palinuro, a medical student, is born into a polygenetic family: Uncle Esteban, who fled from Hungary during the Great War and travelled across the world to Mexico, clinging to his dream of becoming a doctor; Grandpa Francisco, a Freemason and old-time companion of Pancho Villa; Uncle Austin, an ex-British marine; grandmothers, aunts, cousins - an eccentric menage. Since childhood, Palinuro has loved his first cousin, Estefania, with an overwhelming and consuming passion. They indulge their incestuous desire and bizarre fantasies in a room in Plaza Santo Domingo. Drawing from a cultural cornucopia, del Paso propels Palinuro and his companions through the real and imaginary realms of mythology, science, politics, social comment, the arts, advertising and pornography. This labyrinthine tour de force is a fusion of Rabelaisian wit, Swiftian satire, Shakespearean invention and pastiche ranging from Hawthorne to Galdos.